diff --git a/src/act-compat.js b/src/act-compat.js
index c8889e65..ea20e25e 100644
--- a/src/act-compat.js
+++ b/src/act-compat.js
@@ -32,7 +32,7 @@ function getGlobalThis() {
   throw new Error('unable to locate global object')
 }
 
-function setReactActEnvironment(isReactActEnvironment) {
+function setIsReactActEnvironment(isReactActEnvironment) {
   getGlobalThis().IS_REACT_ACT_ENVIRONMENT = isReactActEnvironment
 }
 
@@ -43,7 +43,7 @@ function getIsReactActEnvironment() {
 function withGlobalActEnvironment(actImplementation) {
   return callback => {
     const previousActEnvironment = getIsReactActEnvironment()
-    setReactActEnvironment(true)
+    setIsReactActEnvironment(true)
     try {
       // The return value of `act` is always a thenable.
       let callbackNeedsToBeAwaited = false
@@ -64,24 +64,24 @@ function withGlobalActEnvironment(actImplementation) {
           then: (resolve, reject) => {
             thenable.then(
               returnValue => {
-                setReactActEnvironment(previousActEnvironment)
+                setIsReactActEnvironment(previousActEnvironment)
                 resolve(returnValue)
               },
               error => {
-                setReactActEnvironment(previousActEnvironment)
+                setIsReactActEnvironment(previousActEnvironment)
                 reject(error)
               },
             )
           },
         }
       } else {
-        setReactActEnvironment(previousActEnvironment)
+        setIsReactActEnvironment(previousActEnvironment)
         return actResult
       }
     } catch (error) {
       // Can't be a `finally {}` block since we don't know if we have to immediately restore IS_REACT_ACT_ENVIRONMENT
       // or if we have to await the callback first.
-      setReactActEnvironment(previousActEnvironment)
+      setIsReactActEnvironment(previousActEnvironment)
       throw error
     }
   }
@@ -203,6 +203,10 @@ function asyncAct(cb) {
 }
 
 export default act
-export {asyncAct, setReactActEnvironment, getIsReactActEnvironment}
+export {
+  asyncAct,
+  setIsReactActEnvironment as setReactActEnvironment,
+  getIsReactActEnvironment,
+}
 
 /* eslint no-console:0 */
diff --git a/src/index.js b/src/index.js
index 96fbe155..bb0d0270 100644
--- a/src/index.js
+++ b/src/index.js
@@ -1,3 +1,4 @@
+import {getIsReactActEnvironment, setReactActEnvironment} from './act-compat'
 import {cleanup} from './pure'
 
 // if we're running in a test runner that supports afterEach
@@ -20,6 +21,21 @@ if (typeof process === 'undefined' || !process.env?.RTL_SKIP_AUTO_CLEANUP) {
       cleanup()
     })
   }
+
+  // No test setup with other test runners available
+  /* istanbul ignore else */
+  if (typeof beforeAll === 'function' && typeof afterAll === 'function') {
+    // This matches the behavior of React < 18.
+    let previousIsReactActEnvironment = getIsReactActEnvironment()
+    beforeAll(() => {
+      previousIsReactActEnvironment = getIsReactActEnvironment()
+      setReactActEnvironment(true)
+    })
+
+    afterAll(() => {
+      setReactActEnvironment(previousIsReactActEnvironment)
+    })
+  }
 }
 
 export * from './pure'
diff --git a/tests/setup-env.js b/tests/setup-env.js
index 6a5fcbee..264828a9 100644
--- a/tests/setup-env.js
+++ b/tests/setup-env.js
@@ -1,9 +1 @@
 import '@testing-library/jest-dom/extend-expect'
-
-beforeEach(() => {
-  global.IS_REACT_ACT_ENVIRONMENT = true
-})
-
-afterEach(() => {
-  global.IS_REACT_ACT_ENVIRONMENT = false
-})