diff --git a/internal/compiler/output_columns.go b/internal/compiler/output_columns.go
index 7e0d57abb5..2a38b90db9 100644
--- a/internal/compiler/output_columns.go
+++ b/internal/compiler/output_columns.go
@@ -106,7 +106,8 @@ func outputColumns(qc *QueryCatalog, node ast.Node) ([]*Column, error) {
 			if res.Name != nil {
 				name = *res.Name
 			}
-			// TODO: The TypeCase code has been copied from below. Instead, we need a recurse function to get the type of a node.
+			// TODO: The TypeCase code has been copied from below. Instead, we
+			// need a recurse function to get the type of a node.
 			if tc, ok := n.Defresult.(*ast.TypeCast); ok {
 				if tc.TypeName == nil {
 					return nil, errors.New("no type name type cast")
@@ -236,6 +237,12 @@ func outputColumns(qc *QueryCatalog, node ast.Node) ([]*Column, error) {
 			// TODO Validate column names
 			col := toColumn(n.TypeName)
 			col.Name = name
+			// TODO Add correct, real type inference
+			if constant, ok := n.Arg.(*ast.A_Const); ok {
+				if _, ok := constant.Val.(*ast.Null); ok {
+					col.NotNull = false
+				}
+			}
 			cols = append(cols, col)
 
 		default:
diff --git a/internal/endtoend/testdata/cast_null/pgx/go/db.go b/internal/endtoend/testdata/cast_null/pgx/go/db.go
new file mode 100644
index 0000000000..4559f50a4f
--- /dev/null
+++ b/internal/endtoend/testdata/cast_null/pgx/go/db.go
@@ -0,0 +1,30 @@
+// Code generated by sqlc. DO NOT EDIT.
+
+package querytest
+
+import (
+	"context"
+
+	"github.com/jackc/pgconn"
+	"github.com/jackc/pgx/v4"
+)
+
+type DBTX interface {
+	Exec(context.Context, string, ...interface{}) (pgconn.CommandTag, error)
+	Query(context.Context, string, ...interface{}) (pgx.Rows, error)
+	QueryRow(context.Context, string, ...interface{}) pgx.Row
+}
+
+func New(db DBTX) *Queries {
+	return &Queries{db: db}
+}
+
+type Queries struct {
+	db DBTX
+}
+
+func (q *Queries) WithTx(tx pgx.Tx) *Queries {
+	return &Queries{
+		db: tx,
+	}
+}
diff --git a/internal/endtoend/testdata/cast_null/pgx/go/models.go b/internal/endtoend/testdata/cast_null/pgx/go/models.go
new file mode 100644
index 0000000000..8170fc4b5c
--- /dev/null
+++ b/internal/endtoend/testdata/cast_null/pgx/go/models.go
@@ -0,0 +1,11 @@
+// Code generated by sqlc. DO NOT EDIT.
+
+package querytest
+
+import (
+	"database/sql"
+)
+
+type Foo struct {
+	Bar sql.NullString
+}
diff --git a/internal/endtoend/testdata/cast_null/pgx/go/query.sql.go b/internal/endtoend/testdata/cast_null/pgx/go/query.sql.go
new file mode 100644
index 0000000000..abe11ff3da
--- /dev/null
+++ b/internal/endtoend/testdata/cast_null/pgx/go/query.sql.go
@@ -0,0 +1,50 @@
+// Code generated by sqlc. DO NOT EDIT.
+// source: query.sql
+
+package querytest
+
+import (
+	"context"
+	"database/sql"
+)
+
+const listNullable = `-- name: ListNullable :many
+SELECT
+  NULL::text as a,
+  NULL::integer as b,
+  NULL::bigint as c,
+  NULL::time as d
+FROM foo
+`
+
+type ListNullableRow struct {
+	A sql.NullString
+	B sql.NullInt32
+	C sql.NullInt64
+	D sql.NullTime
+}
+
+func (q *Queries) ListNullable(ctx context.Context) ([]ListNullableRow, error) {
+	rows, err := q.db.Query(ctx, listNullable)
+	if err != nil {
+		return nil, err
+	}
+	defer rows.Close()
+	var items []ListNullableRow
+	for rows.Next() {
+		var i ListNullableRow
+		if err := rows.Scan(
+			&i.A,
+			&i.B,
+			&i.C,
+			&i.D,
+		); err != nil {
+			return nil, err
+		}
+		items = append(items, i)
+	}
+	if err := rows.Err(); err != nil {
+		return nil, err
+	}
+	return items, nil
+}
diff --git a/internal/endtoend/testdata/cast_null/pgx/query.sql b/internal/endtoend/testdata/cast_null/pgx/query.sql
new file mode 100644
index 0000000000..b2a7a6ed81
--- /dev/null
+++ b/internal/endtoend/testdata/cast_null/pgx/query.sql
@@ -0,0 +1,9 @@
+CREATE TABLE foo (bar text);
+
+-- name: ListNullable :many
+SELECT
+  NULL::text as a,
+  NULL::integer as b,
+  NULL::bigint as c,
+  NULL::time as d
+FROM foo;
diff --git a/internal/endtoend/testdata/cast_null/pgx/sqlc.json b/internal/endtoend/testdata/cast_null/pgx/sqlc.json
new file mode 100644
index 0000000000..9403bd0279
--- /dev/null
+++ b/internal/endtoend/testdata/cast_null/pgx/sqlc.json
@@ -0,0 +1,13 @@
+{
+  "version": "1",
+  "packages": [
+    {
+      "path": "go",
+      "engine": "postgresql",
+      "sql_package": "pgx/v4",
+      "name": "querytest",
+      "schema": "query.sql",
+      "queries": "query.sql"
+    }
+  ]
+}
diff --git a/internal/endtoend/testdata/cast_null/stdlib/go/db.go b/internal/endtoend/testdata/cast_null/stdlib/go/db.go
new file mode 100644
index 0000000000..6a99519302
--- /dev/null
+++ b/internal/endtoend/testdata/cast_null/stdlib/go/db.go
@@ -0,0 +1,29 @@
+// Code generated by sqlc. DO NOT EDIT.
+
+package querytest
+
+import (
+	"context"
+	"database/sql"
+)
+
+type DBTX interface {
+	ExecContext(context.Context, string, ...interface{}) (sql.Result, error)
+	PrepareContext(context.Context, string) (*sql.Stmt, error)
+	QueryContext(context.Context, string, ...interface{}) (*sql.Rows, error)
+	QueryRowContext(context.Context, string, ...interface{}) *sql.Row
+}
+
+func New(db DBTX) *Queries {
+	return &Queries{db: db}
+}
+
+type Queries struct {
+	db DBTX
+}
+
+func (q *Queries) WithTx(tx *sql.Tx) *Queries {
+	return &Queries{
+		db: tx,
+	}
+}
diff --git a/internal/endtoend/testdata/cast_null/stdlib/go/models.go b/internal/endtoend/testdata/cast_null/stdlib/go/models.go
new file mode 100644
index 0000000000..8170fc4b5c
--- /dev/null
+++ b/internal/endtoend/testdata/cast_null/stdlib/go/models.go
@@ -0,0 +1,11 @@
+// Code generated by sqlc. DO NOT EDIT.
+
+package querytest
+
+import (
+	"database/sql"
+)
+
+type Foo struct {
+	Bar sql.NullString
+}
diff --git a/internal/endtoend/testdata/cast_null/stdlib/go/query.sql.go b/internal/endtoend/testdata/cast_null/stdlib/go/query.sql.go
new file mode 100644
index 0000000000..73969b570f
--- /dev/null
+++ b/internal/endtoend/testdata/cast_null/stdlib/go/query.sql.go
@@ -0,0 +1,53 @@
+// Code generated by sqlc. DO NOT EDIT.
+// source: query.sql
+
+package querytest
+
+import (
+	"context"
+	"database/sql"
+)
+
+const listNullable = `-- name: ListNullable :many
+SELECT
+  NULL::text as a,
+  NULL::integer as b,
+  NULL::bigint as c,
+  NULL::time as d
+FROM foo
+`
+
+type ListNullableRow struct {
+	A sql.NullString
+	B sql.NullInt32
+	C sql.NullInt64
+	D sql.NullTime
+}
+
+func (q *Queries) ListNullable(ctx context.Context) ([]ListNullableRow, error) {
+	rows, err := q.db.QueryContext(ctx, listNullable)
+	if err != nil {
+		return nil, err
+	}
+	defer rows.Close()
+	var items []ListNullableRow
+	for rows.Next() {
+		var i ListNullableRow
+		if err := rows.Scan(
+			&i.A,
+			&i.B,
+			&i.C,
+			&i.D,
+		); err != nil {
+			return nil, err
+		}
+		items = append(items, i)
+	}
+	if err := rows.Close(); err != nil {
+		return nil, err
+	}
+	if err := rows.Err(); err != nil {
+		return nil, err
+	}
+	return items, nil
+}
diff --git a/internal/endtoend/testdata/cast_null/stdlib/query.sql b/internal/endtoend/testdata/cast_null/stdlib/query.sql
new file mode 100644
index 0000000000..b2a7a6ed81
--- /dev/null
+++ b/internal/endtoend/testdata/cast_null/stdlib/query.sql
@@ -0,0 +1,9 @@
+CREATE TABLE foo (bar text);
+
+-- name: ListNullable :many
+SELECT
+  NULL::text as a,
+  NULL::integer as b,
+  NULL::bigint as c,
+  NULL::time as d
+FROM foo;
diff --git a/internal/endtoend/testdata/cast_null/stdlib/sqlc.json b/internal/endtoend/testdata/cast_null/stdlib/sqlc.json
new file mode 100644
index 0000000000..ac7c2ed829
--- /dev/null
+++ b/internal/endtoend/testdata/cast_null/stdlib/sqlc.json
@@ -0,0 +1,11 @@
+{
+  "version": "1",
+  "packages": [
+    {
+      "path": "go",
+      "name": "querytest",
+      "schema": "query.sql",
+      "queries": "query.sql"
+    }
+  ]
+}