diff --git a/spring-aop/src/main/java/org/springframework/aop/framework/AdvisedSupport.java b/spring-aop/src/main/java/org/springframework/aop/framework/AdvisedSupport.java
index efa0e1e8b5a5..4a963f537c2c 100644
--- a/spring-aop/src/main/java/org/springframework/aop/framework/AdvisedSupport.java
+++ b/spring-aop/src/main/java/org/springframework/aop/framework/AdvisedSupport.java
@@ -391,6 +391,11 @@ protected final List<Advisor> getAdvisorsInternal() {
 		return this.advisors;
 	}
 
+	protected void clearAdvisors() {
+		this.advisors.clear();
+		updateAdvisorArray();
+		adviceChanged();
+	}
 
 	@Override
 	public void addAdvice(Advice advice) throws AopConfigException {
diff --git a/spring-aop/src/main/java/org/springframework/aop/framework/ProxyFactoryBean.java b/spring-aop/src/main/java/org/springframework/aop/framework/ProxyFactoryBean.java
index d224a93a1a6b..408d4c032666 100644
--- a/spring-aop/src/main/java/org/springframework/aop/framework/ProxyFactoryBean.java
+++ b/spring-aop/src/main/java/org/springframework/aop/framework/ProxyFactoryBean.java
@@ -163,6 +163,7 @@ public void setProxyInterfaces(Class<?>[] proxyInterfaces) throws ClassNotFoundE
 	 */
 	public void setInterceptorNames(String... interceptorNames) {
 		this.interceptorNames = interceptorNames;
+		initializeAdvisorChain();
 	}
 
 	/**
@@ -248,7 +249,9 @@ public void setBeanFactory(BeanFactory beanFactory) {
 	 */
 	@Override
 	public Object getObject() throws BeansException {
-		initializeAdvisorChain();
+		if (!this.advisorChainInitialized) {
+			initializeAdvisorChain();
+		}
 		if (isSingleton()) {
 			return getSingletonInstance();
 		}
@@ -430,9 +433,7 @@ private boolean isNamedBeanAnAdvisorOrAdvice(String beanName) {
 	 * are unaffected by such changes.
 	 */
 	private synchronized void initializeAdvisorChain() throws AopConfigException, BeansException {
-		if (this.advisorChainInitialized) {
-			return;
-		}
+		clearAdvisors();
 
 		if (!ObjectUtils.isEmpty(this.interceptorNames)) {
 			if (this.beanFactory == null) {