diff --git a/ext/mysqli/tests/gh12107.phpt b/ext/mysqli/tests/gh12107.phpt
new file mode 100644
index 0000000000000..ca5dd4ba8f142
--- /dev/null
+++ b/ext/mysqli/tests/gh12107.phpt
@@ -0,0 +1,59 @@
+--TEST--
+GH-12107 (When running a stored procedure (that returns a result set) twice, PHP crashes)
+--EXTENSIONS--
+mysqli
+--SKIPIF--
+<?php
+require_once 'skipifconnectfailure.inc';
+?>
+--FILE--
+<?php
+require_once 'connect.inc';
+
+$mysqli = new mysqli("$host:$port", $user, $passwd, $db);
+
+$sql = <<<SQL
+CREATE PROCEDURE `gh12107`()
+BEGIN
+    SELECT "hello world";
+END;
+SQL;
+$mysqli->query($sql);
+
+echo "Start or run 1\n";
+$stmt = $mysqli->prepare("call `gh12107`()");
+$stmt->execute();
+$stmt->bind_result($output);
+var_dump($stmt->fetch());
+var_dump($output);
+unset($output);
+echo "End of run 1\n";
+
+echo "Start or run 2\n";
+$stmt->execute();
+$stmt->bind_result($output);
+var_dump($stmt->fetch());
+var_dump($output);
+echo "End of run 2\n";
+
+?>
+--CLEAN--
+<?php
+require_once 'connect.inc';
+if (!$link = my_mysqli_connect($host, $user, $passwd, $db, $port, $socket))
+   printf("[c001] [%d] %s\n", mysqli_connect_errno(), mysqli_connect_error());
+
+if (!mysqli_query($link, "DROP PROCEDURE IF EXISTS gh12107"))
+    printf("[c002] Cannot drop procedure, [%d] %s\n", mysqli_errno($link), mysqli_error($link));
+
+mysqli_close($link);
+?>
+--EXPECT--
+Start or run 1
+bool(true)
+string(11) "hello world"
+End of run 1
+Start or run 2
+bool(true)
+string(11) "hello world"
+End of run 2
diff --git a/ext/mysqlnd/mysqlnd_ps.c b/ext/mysqlnd/mysqlnd_ps.c
index 15ccec4522beb..10c220bc4b7cb 100644
--- a/ext/mysqlnd/mysqlnd_ps.c
+++ b/ext/mysqlnd/mysqlnd_ps.c
@@ -652,8 +652,11 @@ MYSQLND_METHOD(mysqlnd_stmt, send_execute)(MYSQLND_STMT * const s, const enum_my
 		  Executed, but the user hasn't started to fetch
 		  This will clean also the metadata, but after the EXECUTE call we will
 		  have it again.
+		  stmt->result may be freed by free_stmt_result, transitively called from flush.
 		*/
-		stmt->result->m.free_result_buffers(stmt->result);
+		if (stmt->result) {
+			stmt->result->m.free_result_buffers(stmt->result);
+		}
 
 		stmt->state = MYSQLND_STMT_PREPARED;
 	} else if (stmt->state < MYSQLND_STMT_PREPARED) {