diff --git a/doc/source/whatsnew/v3.0.0.rst b/doc/source/whatsnew/v3.0.0.rst
index a7f63d75a047e..35594b23710e5 100644
--- a/doc/source/whatsnew/v3.0.0.rst
+++ b/doc/source/whatsnew/v3.0.0.rst
@@ -640,6 +640,7 @@ Datetimelike
 - Bug in :meth:`to_datetime` reports incorrect index in case of any failure scenario. (:issue:`58298`)
 - Bug in :meth:`to_datetime` wrongly converts when ``arg`` is a ``np.datetime64`` object with unit of ``ps``. (:issue:`60341`)
 - Bug in setting scalar values with mismatched resolution into arrays with non-nanosecond ``datetime64``, ``timedelta64`` or :class:`DatetimeTZDtype` incorrectly truncating those scalars (:issue:`56410`)
+- BUG: Ensure to_datetime raises errors for out-of-bounds scalar inputs (:issue:`60744`)
 
 Timedelta
 ^^^^^^^^^
diff --git a/pandas/core/tools/datetimes.py b/pandas/core/tools/datetimes.py
index 30487de7bafd5..e9d5baf0f3a2b 100644
--- a/pandas/core/tools/datetimes.py
+++ b/pandas/core/tools/datetimes.py
@@ -481,9 +481,18 @@ def _array_strptime_with_fallback(
 
 def _to_datetime_with_unit(arg, unit, name, utc: bool, errors: str) -> Index:
     """
-    to_datetime specalized to the case where a 'unit' is passed.
+    to_datetime specialized to the case where a 'unit' is passed.
+
+    Note: This function currently treats values at the upper bound differently
+    from values at the lower bound.
+    For upper bound, it raises OutOfBoundsDatetime.
+    For lower bound, it returns NaT.
     """
     arg = extract_array(arg, extract_numpy=True)
+    # Fix GH#60677
+    # Ensure scalar and array-like both become arrays
+    #    (so both paths use the same code).
+    arg = np.atleast_1d(arg)
 
     # GH#30050 pass an ndarray to tslib.array_to_datetime
     # because it expects an ndarray argument
@@ -496,6 +505,31 @@ def _to_datetime_with_unit(arg, unit, name, utc: bool, errors: str) -> Index:
         if arg.dtype.kind in "iu":
             # Note we can't do "f" here because that could induce unwanted
             #  rounding GH#14156, GH#20445
+            # Fix GH#60677
+            # ------------------------------------------------
+            # A) **Check for uint64 values above int64 max**
+            #    so we don't accidentally wrap around to -1, etc.
+            # ------------------------------------------------
+            if arg.dtype.kind == "u":  # unsigned
+                above_max = arg > np.iinfo(np.int64).max
+                if above_max.any():
+                    if errors == "raise":
+                        raise OutOfBoundsDatetime(
+                            "Cannot convert uint64 values above"
+                            f"{np.iinfo(np.int64).max}"
+                            "to a 64-bit signed datetime64[ns]."
+                        )
+                    else:
+                        # For errors != "raise" (e.g. "coerce" or "ignore"),
+                        # we can replace out-of-range entries with NaN (-> NaT),
+                        # then switch to the fallback object path:
+                        arg = arg.astype(object)
+                        arg[above_max] = np.nan
+                        return _to_datetime_with_unit(arg, unit, name, utc, errors)
+
+            # ------------------------------------------------
+            # B) Proceed with normal numeric -> datetime logic
+            # ------------------------------------------------
             arr = arg.astype(f"datetime64[{unit}]", copy=False)
             try:
                 arr = astype_overflowsafe(arr, np.dtype("M8[ns]"), copy=False)
diff --git a/pandas/tests/tools/test_to_datetime.py b/pandas/tests/tools/test_to_datetime.py
index 74b051aec71a4..7901ac955b711 100644
--- a/pandas/tests/tools/test_to_datetime.py
+++ b/pandas/tests/tools/test_to_datetime.py
@@ -3689,3 +3689,30 @@ def test_to_datetime_wrapped_datetime64_ps():
         ["1970-01-01 00:00:01.901901901"], dtype="datetime64[ns]", freq=None
     )
     tm.assert_index_equal(result, expected)
+
+
+def test_to_datetime_scalar_out_of_bounds():
+    """Ensure pd.to_datetime raises an error for out-of-bounds scalar values."""
+    uint64_max = np.iinfo("uint64").max
+    int64_min = np.iinfo("int64").min
+
+    # Expect an OverflowError when passing uint64_max as a scalar
+    with pytest.raises(OutOfBoundsDatetime):
+        to_datetime(uint64_max, unit="ns")
+
+    # Expect the same behavior when passing it as a list
+    with pytest.raises(OutOfBoundsDatetime):
+        to_datetime([uint64_max], unit="ns")
+
+    # Expect NAT  when passing int64_min as a scalar
+    value = to_datetime(int64_min, unit="ns")
+    assert value is NaT
+
+    # Expect the same behavior when passing it as a list
+    value = to_datetime([int64_min], unit="ns")
+    assert value[0] is NaT
+
+    # Test a valid value (should not raise an error)
+    valid_timestamp = 1_700_000_000_000_000_000  # A reasonable nanosecond timestamp
+    result = to_datetime(valid_timestamp, unit="ns")
+    assert isinstance(result, Timestamp)