diff --git a/pandas/io/pytables.py b/pandas/io/pytables.py
index bc99417c67310..b49c1b94b32ac 100644
--- a/pandas/io/pytables.py
+++ b/pandas/io/pytables.py
@@ -568,7 +568,10 @@ def flush(self, fsync=False):
         if self._handle is not None:
             self._handle.flush()
             if fsync:
-                os.fsync(self._handle.fileno())
+                try:
+                    os.fsync(self._handle.fileno())
+                except:
+                    pass
 
     def get(self, key):
         """