diff --git a/pandas/core/arrays/_mixins.py b/pandas/core/arrays/_mixins.py
index 6d21f4a1ac8a2..8fb9e02cc34aa 100644
--- a/pandas/core/arrays/_mixins.py
+++ b/pandas/core/arrays/_mixins.py
@@ -128,17 +128,31 @@ def view(self, dtype: Dtype | None = None) -> ArrayLike:
         dtype = pandas_dtype(dtype)
         arr = self._ndarray
 
-        if isinstance(dtype, (PeriodDtype, DatetimeTZDtype)):
+        if isinstance(dtype, PeriodDtype):
             cls = dtype.construct_array_type()
             return cls(arr.view("i8"), dtype=dtype)
+        elif isinstance(dtype, DatetimeTZDtype):
+            # error: Incompatible types in assignment (expression has type
+            # "type[DatetimeArray]", variable has type "type[PeriodArray]")
+            cls = dtype.construct_array_type()  # type: ignore[assignment]
+            dt64_values = arr.view(f"M8[{dtype.unit}]")
+            return cls(dt64_values, dtype=dtype)
         elif dtype == "M8[ns]":
             from pandas.core.arrays import DatetimeArray
 
-            return DatetimeArray(arr.view("i8"), dtype=dtype)
+            # error: Argument 1 to "view" of "ndarray" has incompatible type
+            # "ExtensionDtype | dtype[Any]"; expected "dtype[Any] | type[Any]
+            # | _SupportsDType[dtype[Any]]"
+            dt64_values = arr.view(dtype)  # type: ignore[arg-type]
+            return DatetimeArray(dt64_values, dtype=dtype)
         elif dtype == "m8[ns]":
             from pandas.core.arrays import TimedeltaArray
 
-            return TimedeltaArray(arr.view("i8"), dtype=dtype)
+            # error: Argument 1 to "view" of "ndarray" has incompatible type
+            # "ExtensionDtype | dtype[Any]"; expected "dtype[Any] | type[Any]
+            # | _SupportsDType[dtype[Any]]"
+            td64_values = arr.view(dtype)  # type: ignore[arg-type]
+            return TimedeltaArray(td64_values, dtype=dtype)
 
         # error: Argument "dtype" to "view" of "_ArrayOrScalarCommon" has incompatible
         # type "Union[ExtensionDtype, dtype[Any]]"; expected "Union[dtype[Any], None,
diff --git a/pandas/core/arrays/datetimelike.py b/pandas/core/arrays/datetimelike.py
index 037e9dd06bb6e..8091543df8e79 100644
--- a/pandas/core/arrays/datetimelike.py
+++ b/pandas/core/arrays/datetimelike.py
@@ -1918,6 +1918,9 @@ class TimelikeOps(DatetimeLikeArrayMixin):
     def __init__(
         self, values, dtype=None, freq=lib.no_default, copy: bool = False
     ) -> None:
+        if dtype is not None:
+            dtype = pandas_dtype(dtype)
+
         values = extract_array(values, extract_numpy=True)
         if isinstance(values, IntegerArray):
             values = values.to_numpy("int64", na_value=iNaT)
@@ -1936,13 +1939,11 @@ def __init__(
                 freq = to_offset(freq)
                 freq, _ = validate_inferred_freq(freq, values.freq, False)
 
-            if dtype is not None:
-                dtype = pandas_dtype(dtype)
-                if dtype != values.dtype:
-                    # TODO: we only have tests for this for DTA, not TDA (2022-07-01)
-                    raise TypeError(
-                        f"dtype={dtype} does not match data dtype {values.dtype}"
-                    )
+            if dtype is not None and dtype != values.dtype:
+                # TODO: we only have tests for this for DTA, not TDA (2022-07-01)
+                raise TypeError(
+                    f"dtype={dtype} does not match data dtype {values.dtype}"
+                )
 
             dtype = values.dtype
             values = values._ndarray
@@ -1952,6 +1953,8 @@ def __init__(
                 dtype = values.dtype
             else:
                 dtype = self._default_dtype
+                if isinstance(values, np.ndarray) and values.dtype == "i8":
+                    values = values.view(dtype)
 
         if not isinstance(values, np.ndarray):
             raise ValueError(
@@ -1966,7 +1969,15 @@ def __init__(
             # for compat with datetime/timedelta/period shared methods,
             #  we can sometimes get here with int64 values.  These represent
             #  nanosecond UTC (or tz-naive) unix timestamps
-            values = values.view(self._default_dtype)
+            if dtype is None:
+                dtype = self._default_dtype
+                values = values.view(self._default_dtype)
+            elif lib.is_np_dtype(dtype, "mM"):
+                values = values.view(dtype)
+            elif isinstance(dtype, DatetimeTZDtype):
+                kind = self._default_dtype.kind
+                new_dtype = f"{kind}8[{dtype.unit}]"
+                values = values.view(new_dtype)
 
         dtype = self._validate_dtype(values, dtype)
 
diff --git a/pandas/core/arrays/datetimes.py b/pandas/core/arrays/datetimes.py
index 23ff5e7491ada..3431de01cb77e 100644
--- a/pandas/core/arrays/datetimes.py
+++ b/pandas/core/arrays/datetimes.py
@@ -278,8 +278,15 @@ def _from_scalars(cls, scalars, *, dtype: DtypeObj) -> Self:
     @classmethod
     def _validate_dtype(cls, values, dtype):
         # used in TimeLikeOps.__init__
-        _validate_dt64_dtype(values.dtype)
         dtype = _validate_dt64_dtype(dtype)
+        _validate_dt64_dtype(values.dtype)
+        if isinstance(dtype, np.dtype):
+            if values.dtype != dtype:
+                raise ValueError("Values resolution does not match dtype.")
+        else:
+            vunit = np.datetime_data(values.dtype)[0]
+            if vunit != dtype.unit:
+                raise ValueError("Values resolution does not match dtype.")
         return dtype
 
     # error: Signature of "_simple_new" incompatible with supertype "NDArrayBacked"
diff --git a/pandas/core/arrays/timedeltas.py b/pandas/core/arrays/timedeltas.py
index ca908c11a97bb..128f1c73062c0 100644
--- a/pandas/core/arrays/timedeltas.py
+++ b/pandas/core/arrays/timedeltas.py
@@ -205,8 +205,10 @@ def dtype(self) -> np.dtype[np.timedelta64]:  # type: ignore[override]
     @classmethod
     def _validate_dtype(cls, values, dtype):
         # used in TimeLikeOps.__init__
-        _validate_td64_dtype(values.dtype)
         dtype = _validate_td64_dtype(dtype)
+        _validate_td64_dtype(values.dtype)
+        if dtype != values.dtype:
+            raise ValueError("Values resolution does not match dtype.")
         return dtype
 
     # error: Signature of "_simple_new" incompatible with supertype "NDArrayBacked"
@@ -1202,11 +1204,9 @@ def _validate_td64_dtype(dtype) -> DtypeObj:
         )
         raise ValueError(msg)
 
-    if (
-        not isinstance(dtype, np.dtype)
-        or dtype.kind != "m"
-        or not is_supported_unit(get_unit_from_dtype(dtype))
-    ):
-        raise ValueError(f"dtype {dtype} cannot be converted to timedelta64[ns]")
+    if not lib.is_np_dtype(dtype, "m"):
+        raise ValueError(f"dtype '{dtype}' is invalid, should be np.timedelta64 dtype")
+    elif not is_supported_unit(get_unit_from_dtype(dtype)):
+        raise ValueError("Supported timedelta64 resolutions are 's', 'ms', 'us', 'ns'")
 
     return dtype
diff --git a/pandas/core/internals/managers.py b/pandas/core/internals/managers.py
index c26e3a88951a8..9f6ac1306d8a6 100644
--- a/pandas/core/internals/managers.py
+++ b/pandas/core/internals/managers.py
@@ -2307,7 +2307,8 @@ def make_na_array(dtype: DtypeObj, shape: Shape, fill_value) -> ArrayLike:
         # NB: exclude e.g. pyarrow[dt64tz] dtypes
         ts = Timestamp(fill_value).as_unit(dtype.unit)
         i8values = np.full(shape, ts._value)
-        return DatetimeArray(i8values, dtype=dtype)
+        dt64values = i8values.view(f"M8[{dtype.unit}]")
+        return DatetimeArray(dt64values, dtype=dtype)
 
     elif is_1d_only_ea_dtype(dtype):
         dtype = cast(ExtensionDtype, dtype)
diff --git a/pandas/core/tools/datetimes.py b/pandas/core/tools/datetimes.py
index c2794dab74e00..3d8b043a90bd1 100644
--- a/pandas/core/tools/datetimes.py
+++ b/pandas/core/tools/datetimes.py
@@ -494,7 +494,9 @@ def _convert_listlike_datetimes(
     if tz_parsed is not None:
         # We can take a shortcut since the datetime64 numpy array
         # is in UTC
-        dta = DatetimeArray(result, dtype=tz_to_dtype(tz_parsed))
+        dtype = cast(DatetimeTZDtype, tz_to_dtype(tz_parsed))
+        dt64_values = result.view(f"M8[{dtype.unit}]")
+        dta = DatetimeArray(dt64_values, dtype=dtype)
         return DatetimeIndex._simple_new(dta, name=name)
 
     return _box_as_indexlike(result, utc=utc, name=name)
diff --git a/pandas/tests/arrays/datetimes/test_constructors.py b/pandas/tests/arrays/datetimes/test_constructors.py
index b0a15d7ef4935..3509206cccb82 100644
--- a/pandas/tests/arrays/datetimes/test_constructors.py
+++ b/pandas/tests/arrays/datetimes/test_constructors.py
@@ -112,6 +112,24 @@ def test_incorrect_dtype_raises(self):
         with pytest.raises(ValueError, match="Unexpected value for 'dtype'."):
             DatetimeArray(np.array([1, 2, 3], dtype="i8"), dtype="category")
 
+        with pytest.raises(ValueError, match="Unexpected value for 'dtype'."):
+            DatetimeArray(np.array([1, 2, 3], dtype="i8"), dtype="m8[s]")
+
+        with pytest.raises(ValueError, match="Unexpected value for 'dtype'."):
+            DatetimeArray(np.array([1, 2, 3], dtype="i8"), dtype="M8[D]")
+
+    def test_mismatched_values_dtype_units(self):
+        arr = np.array([1, 2, 3], dtype="M8[s]")
+        dtype = np.dtype("M8[ns]")
+        msg = "Values resolution does not match dtype."
+
+        with pytest.raises(ValueError, match=msg):
+            DatetimeArray(arr, dtype=dtype)
+
+        dtype2 = DatetimeTZDtype(tz="UTC", unit="ns")
+        with pytest.raises(ValueError, match=msg):
+            DatetimeArray(arr, dtype=dtype2)
+
     def test_freq_infer_raises(self):
         with pytest.raises(ValueError, match="Frequency inference"):
             DatetimeArray(np.array([1, 2, 3], dtype="i8"), freq="infer")
diff --git a/pandas/tests/arrays/test_datetimes.py b/pandas/tests/arrays/test_datetimes.py
index c2d68a79f32d4..c9804615ba903 100644
--- a/pandas/tests/arrays/test_datetimes.py
+++ b/pandas/tests/arrays/test_datetimes.py
@@ -468,7 +468,7 @@ def test_repeat_preserves_tz(self):
         repeated = arr.repeat([1, 1])
 
         # preserves tz and values, but not freq
-        expected = DatetimeArray(arr.asi8, freq=None, dtype=arr.dtype)
+        expected = DatetimeArray._from_sequence(arr.asi8, dtype=arr.dtype)
         tm.assert_equal(repeated, expected)
 
     def test_value_counts_preserves_tz(self):
diff --git a/pandas/tests/arrays/timedeltas/test_constructors.py b/pandas/tests/arrays/timedeltas/test_constructors.py
index 3a076a6828a98..30894becc35cf 100644
--- a/pandas/tests/arrays/timedeltas/test_constructors.py
+++ b/pandas/tests/arrays/timedeltas/test_constructors.py
@@ -33,21 +33,40 @@ def test_non_array_raises(self):
             TimedeltaArray([1, 2, 3])
 
     def test_other_type_raises(self):
-        with pytest.raises(ValueError, match="dtype bool cannot be converted"):
+        msg = "dtype 'bool' is invalid, should be np.timedelta64 dtype"
+        with pytest.raises(ValueError, match=msg):
             TimedeltaArray(np.array([1, 2, 3], dtype="bool"))
 
     def test_incorrect_dtype_raises(self):
-        # TODO: why TypeError for 'category' but ValueError for i8?
-        with pytest.raises(
-            ValueError, match=r"category cannot be converted to timedelta64\[ns\]"
-        ):
+        msg = "dtype 'category' is invalid, should be np.timedelta64 dtype"
+        with pytest.raises(ValueError, match=msg):
             TimedeltaArray(np.array([1, 2, 3], dtype="i8"), dtype="category")
 
-        with pytest.raises(
-            ValueError, match=r"dtype int64 cannot be converted to timedelta64\[ns\]"
-        ):
+        msg = "dtype 'int64' is invalid, should be np.timedelta64 dtype"
+        with pytest.raises(ValueError, match=msg):
             TimedeltaArray(np.array([1, 2, 3], dtype="i8"), dtype=np.dtype("int64"))
 
+        msg = r"dtype 'datetime64\[ns\]' is invalid, should be np.timedelta64 dtype"
+        with pytest.raises(ValueError, match=msg):
+            TimedeltaArray(np.array([1, 2, 3], dtype="i8"), dtype=np.dtype("M8[ns]"))
+
+        msg = (
+            r"dtype 'datetime64\[us, UTC\]' is invalid, should be np.timedelta64 dtype"
+        )
+        with pytest.raises(ValueError, match=msg):
+            TimedeltaArray(np.array([1, 2, 3], dtype="i8"), dtype="M8[us, UTC]")
+
+        msg = "Supported timedelta64 resolutions are 's', 'ms', 'us', 'ns'"
+        with pytest.raises(ValueError, match=msg):
+            TimedeltaArray(np.array([1, 2, 3], dtype="i8"), dtype=np.dtype("m8[Y]"))
+
+    def test_mismatched_values_dtype_units(self):
+        arr = np.array([1, 2, 3], dtype="m8[s]")
+        dtype = np.dtype("m8[ns]")
+        msg = r"Values resolution does not match dtype"
+        with pytest.raises(ValueError, match=msg):
+            TimedeltaArray(arr, dtype=dtype)
+
     def test_copy(self):
         data = np.array([1, 2, 3], dtype="m8[ns]")
         arr = TimedeltaArray(data, copy=False)
@@ -58,6 +77,6 @@ def test_copy(self):
         assert arr._ndarray.base is not data
 
     def test_from_sequence_dtype(self):
-        msg = "dtype .*object.* cannot be converted to timedelta64"
+        msg = "dtype 'object' is invalid, should be np.timedelta64 dtype"
         with pytest.raises(ValueError, match=msg):
             TimedeltaArray._from_sequence([], dtype=object)
diff --git a/pandas/tests/base/test_conversion.py b/pandas/tests/base/test_conversion.py
index c0f65c23c6d35..7589517f417e8 100644
--- a/pandas/tests/base/test_conversion.py
+++ b/pandas/tests/base/test_conversion.py
@@ -314,7 +314,9 @@ def test_array_multiindex_raises():
         ),
         # Timedelta
         (
-            TimedeltaArray(np.array([0, 3600000000000], dtype="i8"), freq="h"),
+            TimedeltaArray(
+                np.array([0, 3600000000000], dtype="i8").view("m8[ns]"), freq="h"
+            ),
             np.array([0, 3600000000000], dtype="m8[ns]"),
         ),
         # GH#26406 tz is preserved in Categorical[dt64tz]
diff --git a/pandas/tests/indexes/timedeltas/test_constructors.py b/pandas/tests/indexes/timedeltas/test_constructors.py
index c173864b1a8b3..ccbd61c4d6693 100644
--- a/pandas/tests/indexes/timedeltas/test_constructors.py
+++ b/pandas/tests/indexes/timedeltas/test_constructors.py
@@ -240,7 +240,7 @@ def test_constructor_no_precision_raises(self):
             pd.Index(["2000"], dtype="timedelta64")
 
     def test_constructor_wrong_precision_raises(self):
-        msg = r"dtype timedelta64\[D\] cannot be converted to timedelta64\[ns\]"
+        msg = "Supported timedelta64 resolutions are 's', 'ms', 'us', 'ns'"
         with pytest.raises(ValueError, match=msg):
             TimedeltaIndex(["2000"], dtype="timedelta64[D]")