diff --git a/pandas/core/algorithms.py b/pandas/core/algorithms.py
index 14dee202a9d8d..549a5144a4053 100644
--- a/pandas/core/algorithms.py
+++ b/pandas/core/algorithms.py
@@ -73,6 +73,7 @@
     na_value_for_dtype,
 )
 
+from pandas.core.api import PeriodDtype
 from pandas.core.array_algos.take import take_nd
 from pandas.core.construction import (
     array as pd_array,
@@ -501,6 +502,8 @@ def isin(comps: ListLike, values: ListLike) -> npt.NDArray[np.bool_]:
     comps_array = extract_array(comps_array, extract_numpy=True)
     if not isinstance(comps_array, np.ndarray):
         # i.e. Extension Array
+        if isinstance(comps_array.dtype, PeriodDtype):
+            comps_array = comps_array.to_timestamp()
         return comps_array.isin(values)
 
     elif needs_i8_conversion(comps_array.dtype):
diff --git a/pandas/tests/arrays/categorical/test_algos.py b/pandas/tests/arrays/categorical/test_algos.py
index d4c19a4970135..ac4025a1a1a92 100644
--- a/pandas/tests/arrays/categorical/test_algos.py
+++ b/pandas/tests/arrays/categorical/test_algos.py
@@ -77,6 +77,22 @@ def test_isin_empty(empty):
     tm.assert_numpy_array_equal(expected, result)
 
 
+def test_isin_period_range():
+    period_range = pd.period_range("2000-01-01", periods=3)
+    element = ["2000-01-02"]
+    result = period_range.isin(element)
+    expected = np.array([False, True, False], dtype=bool)
+    tm.assert_numpy_array_equal(expected, result)
+
+
+def test_isin_date_dtype():
+    period_range = pd.date_range("2000-01-01", periods=3)
+    element = ["2000-01-02"]
+    result = period_range.isin(element)
+    expected = np.array([False, True, False], dtype=bool)
+    tm.assert_numpy_array_equal(expected, result)
+
+
 def test_diff():
     ser = pd.Series([1, 2, 3], dtype="category")
 
diff --git a/pandas/tests/frame/test_query_eval.py b/pandas/tests/frame/test_query_eval.py
index 72e8236159bda..b12f883aac74b 100644
--- a/pandas/tests/frame/test_query_eval.py
+++ b/pandas/tests/frame/test_query_eval.py
@@ -16,6 +16,7 @@
     MultiIndex,
     Series,
     date_range,
+    period_range,
 )
 import pandas._testing as tm
 from pandas.core.computation.check import NUMEXPR_INSTALLED
@@ -1404,3 +1405,21 @@ def test_query_ea_equality_comparison(self, dtype, engine):
             }
         )
         tm.assert_frame_equal(result, expected)
+
+
+class TestPeriodDtypeQueryPythonPandas(TestDataFrameQueryNumExprPandas):
+    @pytest.fixture
+    def engine(self):
+        return "python"
+
+    @pytest.fixture
+    def parser(self):
+        return "pandas"
+
+    def test_query_builtin(self, engine, parser):
+        df = DataFrame(
+            {"Date": period_range("2000-01-01", periods=10, name="Date")},
+        )
+        result = df.query("Date == '2000-01-06'", parser=parser, engine=engine)
+        expected = DataFrame([{"Date": pd.Period("2000-01-06", "D")}], index=[5])
+        tm.assert_frame_equal(result, expected)