diff --git a/asv_bench/benchmarks/groupby.py b/asv_bench/benchmarks/groupby.py
index 97f48a3a6f69f..2225cbd74d718 100644
--- a/asv_bench/benchmarks/groupby.py
+++ b/asv_bench/benchmarks/groupby.py
@@ -14,6 +14,7 @@
     Timestamp,
     date_range,
     period_range,
+    to_timedelta,
 )
 
 from .pandas_vb_common import tm
@@ -987,4 +988,31 @@ def time_sample_weights(self):
         self.df.groupby(self.groups).sample(n=1, weights=self.weights)
 
 
+class Resample:
+    # GH 28635
+    def setup(self):
+        num_timedeltas = 20_000
+        num_groups = 3
+
+        index = MultiIndex.from_product(
+            [
+                np.arange(num_groups),
+                to_timedelta(np.arange(num_timedeltas), unit="s"),
+            ],
+            names=["groups", "timedeltas"],
+        )
+        data = np.random.randint(0, 1000, size=(len(index)))
+
+        self.df = DataFrame(data, index=index).reset_index("timedeltas")
+        self.df_multiindex = DataFrame(data, index=index)
+
+    def time_resample(self):
+        self.df.groupby(level="groups").resample("10s", on="timedeltas").mean()
+
+    def time_resample_multiindex(self):
+        self.df_multiindex.groupby(level="groups").resample(
+            "10s", level="timedeltas"
+        ).mean()
+
+
 from .pandas_vb_common import setup  # noqa: F401 isort:skip