diff --git a/.github/workflows/asv-bot.yml b/.github/workflows/asv-bot.yml
index c2a49dd96c1c1..26249b41870f7 100644
--- a/.github/workflows/asv-bot.yml
+++ b/.github/workflows/asv-bot.yml
@@ -43,6 +43,8 @@ jobs:
         # during discovery process
       - uses: conda-incubator/setup-miniconda@v2
         with:
+          mamba-version: "*"
+          channels: conda-forge,defaults
           activate-environment: pandas-dev
           channel-priority: strict
           environment-file: ${{ env.ENV_FILE }}
diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 0bb82ed5d6816..b97682ac38b2d 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -41,6 +41,8 @@ jobs:
 
     - uses: conda-incubator/setup-miniconda@v2
       with:
+        mamba-version: "*"
+        channels: conda-forge,defaults
         activate-environment: pandas-dev
         channel-priority: strict
         environment-file: ${{ env.ENV_FILE }}
@@ -104,6 +106,8 @@ jobs:
 
     - uses: conda-incubator/setup-miniconda@v2
       with:
+        mamba-version: "*"
+        channels: conda-forge,defaults
         activate-environment: pandas-dev
         channel-priority: strict
         environment-file: ${{ env.ENV_FILE }}
diff --git a/.github/workflows/database.yml b/.github/workflows/database.yml
index 3fdca951ae058..f937d7b289351 100644
--- a/.github/workflows/database.yml
+++ b/.github/workflows/database.yml
@@ -88,6 +88,8 @@ jobs:
 
     - uses: conda-incubator/setup-miniconda@v2
       with:
+        mamba-version: "*"
+        channels: conda-forge,defaults
         activate-environment: pandas-dev
         channel-priority: strict
         environment-file: ${{ matrix.ENV_FILE }}
diff --git a/.github/workflows/posix.yml b/.github/workflows/posix.yml
index 9839eacc046f9..251514d39424f 100644
--- a/.github/workflows/posix.yml
+++ b/.github/workflows/posix.yml
@@ -81,6 +81,8 @@ jobs:
 
     - uses: conda-incubator/setup-miniconda@v2
       with:
+        mamba-version: "*"
+        channels: conda-forge,defaults
         activate-environment: pandas-dev
         channel-priority: flexible
         environment-file: ${{ env.ENV_FILE }}
diff --git a/.github/workflows/python-dev.yml b/.github/workflows/python-dev.yml
index 8b3a5a23d7a97..0923888bf8e4e 100644
--- a/.github/workflows/python-dev.yml
+++ b/.github/workflows/python-dev.yml
@@ -48,7 +48,7 @@ jobs:
     - name: Install dependencies
       shell: bash
       run: |
-        python -m pip install --upgrade pip setuptools wheel
+        python -m pip install --upgrade pip "setuptools<60.0.0" wheel
         pip install -i https://pypi.anaconda.org/scipy-wheels-nightly/simple numpy
         pip install git+https://github.com/nedbat/coveragepy.git
         pip install cython python-dateutil pytz hypothesis pytest>=6.2.5 pytest-xdist pytest-cov
diff --git a/.github/workflows/sdist.yml b/.github/workflows/sdist.yml
index 5fc447a395aea..9e54397cee337 100644
--- a/.github/workflows/sdist.yml
+++ b/.github/workflows/sdist.yml
@@ -53,6 +53,8 @@ jobs:
 
     - uses: conda-incubator/setup-miniconda@v2
       with:
+        mamba-version: "*"
+        channels: conda-forge,defaults
         activate-environment: pandas-sdist
         channels: conda-forge
         python-version: '${{ matrix.python-version }}'
diff --git a/ci/deps/actions-38-db.yaml b/ci/deps/actions-38-db.yaml
index c08c642049b41..826a05fbaea63 100644
--- a/ci/deps/actions-38-db.yaml
+++ b/ci/deps/actions-38-db.yaml
@@ -30,7 +30,7 @@ dependencies:
   - openpyxl
   - pandas-gbq
   - psycopg2
-  - pyarrow>=1.0.1
+  - pyarrow>2
   - pymysql
   - pytables
   - python-snappy
diff --git a/ci/deps/actions-39-slow.yaml b/ci/deps/actions-39-slow.yaml
index cb54210e81f23..6970ebb43515d 100644
--- a/ci/deps/actions-39-slow.yaml
+++ b/ci/deps/actions-39-slow.yaml
@@ -26,7 +26,7 @@ dependencies:
   - numexpr
   - numpy
   - openpyxl
-  - pyarrow
+  - pyarrow>2
   - pytables
   - python-dateutil
   - pytz
diff --git a/ci/deps/actions-39.yaml b/ci/deps/actions-39.yaml
index dc897453114f1..053443b478aa2 100644
--- a/ci/deps/actions-39.yaml
+++ b/ci/deps/actions-39.yaml
@@ -21,11 +21,11 @@ dependencies:
   - jinja2
   - lxml
   - matplotlib
+  - numpy
   - numba
   - numexpr
-  - numpy
   - openpyxl
-  - pyarrow
+  - pyarrow>2
   - pytables
   - python-dateutil
   - pytz
diff --git a/ci/deps/azure-windows-39.yaml b/ci/deps/azure-windows-39.yaml
index a0dde78c37261..0dbebc9885c5b 100644
--- a/ci/deps/azure-windows-39.yaml
+++ b/ci/deps/azure-windows-39.yaml
@@ -25,7 +25,7 @@ dependencies:
   - numexpr
   - numpy
   - openpyxl
-  - pyarrow
+  - pyarrow>2
   - pytables
   - python-dateutil
   - pytz
diff --git a/ci/setup_env.sh b/ci/setup_env.sh
index 2e16bc6545161..a967ecb274d0c 100755
--- a/ci/setup_env.sh
+++ b/ci/setup_env.sh
@@ -48,6 +48,7 @@ conda config --set ssl_verify false
 conda config --set quiet true --set always_yes true --set changeps1 false
 conda install pip conda  # create conda to create a historical artifact for pip & setuptools
 conda update -n base conda
+conda install -y -c conda-forge mamba
 
 echo "conda info -a"
 conda info -a
@@ -62,8 +63,8 @@ conda list
 conda remove --all -q -y -n pandas-dev
 
 echo
-echo "conda env create -q --file=${ENV_FILE}"
-time conda env create -q --file="${ENV_FILE}"
+echo "mamba env create -q --file=${ENV_FILE}"
+time mamba env create -q --file="${ENV_FILE}"
 
 
 if [[ "$BITS32" == "yes" ]]; then
@@ -106,7 +107,7 @@ echo "[Build extensions]"
 python setup.py build_ext -q -j2
 
 echo "[Updating pip]"
-python -m pip install --no-deps -U pip wheel setuptools
+python -m pip install --no-deps -U pip wheel "setuptools<60.0.0"
 
 echo "[Install pandas]"
 python -m pip install --no-build-isolation -e .
diff --git a/environment.yml b/environment.yml
index 30d05ab7700ff..c235f3d09e50d 100644
--- a/environment.yml
+++ b/environment.yml
@@ -100,7 +100,7 @@ dependencies:
   - odfpy
 
   - fastparquet>=0.4.0  # pandas.read_parquet, DataFrame.to_parquet
-  - pyarrow>=1.0.1  # pandas.read_parquet, DataFrame.to_parquet, pandas.read_feather, DataFrame.to_feather
+  - pyarrow>2  # pandas.read_parquet, DataFrame.to_parquet, pandas.read_feather, DataFrame.to_feather
   - python-snappy  # required by pyarrow
 
   - pytables>=3.6.1  # pandas.read_hdf, DataFrame.to_hdf