diff --git a/pandas/core/series.py b/pandas/core/series.py
index 4194cbd4e4156..b6e1448514112 100644
--- a/pandas/core/series.py
+++ b/pandas/core/series.py
@@ -110,7 +110,10 @@ def na_op(x, y):
                 y = lib.list_to_object_array(y)
 
             if isinstance(y, np.ndarray):
-                result = lib.vec_compare(x, y, op)
+                if y.dtype != np.object_:
+                    result = lib.vec_compare(x, y.astype(np.object_), op)
+                else:
+                    result = lib.vec_compare(x, y, op)
             else:
                 result = lib.scalar_compare(x, y, op)
         else: