diff --git a/.github/workflows/comment_commands.yml b/.github/workflows/comment_commands.yml
new file mode 100644
index 000000000..c85cdca8e
--- /dev/null
+++ b/.github/workflows/comment_commands.yml
@@ -0,0 +1,71 @@
+name: Comment Commands to Trigger CI
+on:
+  issue_comment:
+    types: created
+
+permissions:
+  checks: write
+
+env:
+  # store mapping of commands to use with poetry
+  RUN_COMMAND: '{"/pandas_nightly": "pytest --nightly", "/pyright_strict": "pyright_strict", "/mypy_nightly": "mypy --mypy_nightly"}'
+  # store mapping of labels to display in the check runs
+  DISPLAY_COMMAND: '{"/pandas_nightly": "Pandas nightly tests", "/pyright_strict": "Pyright strict tests", "/mypy_nightly": "Mypy nightly tests"}'
+
+jobs:
+  optional_tests:
+    name: "Optional tests run"
+    runs-on: ubuntu-latest
+    timeout-minutes: 10
+    # if more commands are added, they will need to be added here too as we don't have access to env at this stage
+    if: (github.event.issue.pull_request) && contains(fromJSON('["/pandas_nightly", "/pyright_strict", "/mypy_nightly"]'), github.event.comment.body)
+
+    steps:
+      - uses: actions/checkout@v4
+
+      - name: Install project dependencies
+        uses: ./.github/setup
+        with:
+          os: ubuntu-latest
+          python-version: "3.11"
+
+      - name: Run ${{ fromJSON(env.DISPLAY_COMMAND)[github.event.comment.body] }}
+        # run the tests based on the value of the comment
+        id: tests-step
+        run: poetry run poe ${{ fromJSON(env.RUN_COMMAND)[github.event.comment.body] }}
+
+      - name: Get head sha and store value
+        # get the sha of the last commit to attach the results of the tests
+        if: always()
+        id: get-sha
+        uses: actions/github-script@v7
+        with:
+          github-token: ${{ secrets.GITHUB_TOKEN }}
+          script: |
+            const pr = await github.rest.pulls.get({
+              owner: context.repo.owner,
+              repo: context.repo.repo,
+              pull_number: ${{ github.event.issue.number }}
+            })
+            core.setOutput('sha', pr.data.head.sha)
+
+      - name: Report results of the tests and publish
+        # publish the results to a check run no matter the pass or fail
+        if: always()
+        uses: actions/github-script@v7
+        with:
+          github-token: ${{ secrets.GITHUB_TOKEN }}
+          script: |
+            github.rest.checks.create({
+              name: '${{ fromJSON(env.DISPLAY_COMMAND)[github.event.comment.body] }}',
+              head_sha: '${{ steps.get-sha.outputs.sha }}',
+              status: 'completed',
+              conclusion: '${{ steps.tests-step.outcome }}',
+              output: {
+                title: 'Run ${{ fromJSON(env.DISPLAY_COMMAND)[github.event.comment.body] }}',
+                summary: 'Results: ${{ steps.tests-step.outcome }}',
+                text: 'See the actions run at ${{ github.server_url }}/${{ github.repository }}/actions/runs/${{ github.run_id }}',
+              },
+              owner: context.repo.owner,
+              repo: context.repo.repo
+            })
diff --git a/docs/tests.md b/docs/tests.md
index fdf2dd5e8..4101bc83e 100644
--- a/docs/tests.md
+++ b/docs/tests.md
@@ -5,7 +5,7 @@
 Here are the most important options. Fore more details, please use `poe --help`.
 
 - Run all tests (against both source and installed stubs): `poe test_all`
-- Run tests against the source code: `poe test` 
+- Run tests against the source code: `poe test`
   - Run only mypy: `poe mypy`
   - Run only pyright: `poe pyright`
   - Run only pytest: `poe pytest`
@@ -20,3 +20,9 @@ The following tests are **optional**. Some of them are run by the CI but it is o
 - Use mypy nightly to validate the annotations: `poe mypy --mypy_nightly`
 - Use pyright in full strict mode: `poe pyright_strict`
 - Run stubtest to compare the installed pandas-stubs against pandas (this will fail): `poe stubtest`. If you have created an allowlist to ignore certain errors: `poe stubtest path_to_the_allow_list`
+
+Among the tests above, the following can be run directly during a PR by commenting in the discussion.
+
+- Run pytest against pandas nightly by commenting `/pandas_nightly`
+- Use mypy nightly to validate the annotations by commenting `/mypy_nightly`
+- Use pyright in full strict mode by commenting `/pyright_strict`