diff --git a/Makefile b/Makefile
index 0e1e927232..095452210a 100644
--- a/Makefile
+++ b/Makefile
@@ -3,7 +3,6 @@
 # rsync -e ssh nipype-0.1-py2.5.egg cburns,nipy@frs.sourceforge.net:/home/frs/project/n/ni/nipy/nipype/nipype-0.1/
 
 PYTHON ?= python
-NOSETESTS=`which nosetests`
 
 .PHONY: zipdoc sdist egg upload_to_pypi trailing-spaces clean-pyc clean-so clean-build clean-ctags clean in inplace test-code test-coverage test html specs check-before-commit check gen-base-dockerfile gen-main-dockerfile gen-dockerfiles
 
diff --git a/Vagrantfile b/Vagrantfile
index 1ee1103ca7..3cd69befe9 100644
--- a/Vagrantfile
+++ b/Vagrantfile
@@ -27,7 +27,7 @@ echo "export PATH=$HOME/miniconda3/bin:\\$PATH" >> .bashrc
 
 # install nipype dependencies
 $HOME/miniconda3/bin/conda update --yes conda
-$HOME/miniconda3/bin/conda install --yes pip scipy nose networkx lxml future simplejson
+$HOME/miniconda3/bin/conda install --yes pip scipy networkx lxml future simplejson
 $HOME/miniconda3/bin/conda install --yes python-dateutil jupyter matplotlib
 $HOME/miniconda3/bin/pip install nibabel
 $HOME/miniconda3/bin/pip install prov
diff --git a/doc/links_names.txt b/doc/links_names.txt
index bd33e1b672..1197917cba 100644
--- a/doc/links_names.txt
+++ b/doc/links_names.txt
@@ -56,7 +56,6 @@
 .. _doctest-mode: http://www.cis.upenn.edu/~edloper/projects/doctestmode/
 .. _bazaar: http://bazaar-vcs.org/
 .. _subversion: http://subversion.tigris.org/
-.. _nose: http://nose.readthedocs.io/en/latest/
 .. _`python coverage tester`: http://nedbatchelder.com/code/modules/coverage.html
 
 .. Other python projects
diff --git a/nipype/pipeline/plugins/tests/test_base.py b/nipype/pipeline/plugins/tests/test_base.py
index 49928cfe4b..cdc55b668b 100644
--- a/nipype/pipeline/plugins/tests/test_base.py
+++ b/nipype/pipeline/plugins/tests/test_base.py
@@ -16,7 +16,7 @@ def test_scipy_sparse():
 
 '''
 Can use the following code to test that a mapnode crash continues successfully
-Need to put this into a nose-test with a timeout
+Need to put this into a unit-test with a timeout
 
 import nipype.interfaces.utility as niu
 import nipype.pipeline.engine as pe
diff --git a/nipype/pipeline/plugins/tests/test_tools.py b/nipype/pipeline/plugins/tests/test_tools.py
index 49b2de63dc..ee9b2e4de7 100644
--- a/nipype/pipeline/plugins/tests/test_tools.py
+++ b/nipype/pipeline/plugins/tests/test_tools.py
@@ -38,7 +38,7 @@ def test_report_crash():
 
 '''
 Can use the following code to test that a mapnode crash continues successfully
-Need to put this into a nose-test with a timeout
+Need to put this into a unit-test with a timeout
 
 import nipype.interfaces.utility as niu
 import nipype.pipeline.engine as pe