diff --git a/examples/wiring/example.py b/examples/wiring/example.py
index 4221ab13..0e32b192 100644
--- a/examples/wiring/example.py
+++ b/examples/wiring/example.py
@@ -2,10 +2,10 @@
 
 from dependency_injector import containers, providers
 from dependency_injector.wiring import Provide, inject
+from typing import Annotated
 
 
-class Service:
-    ...
+class Service: ...
 
 
 class Container(containers.DeclarativeContainer):
@@ -13,9 +13,16 @@ class Container(containers.DeclarativeContainer):
     service = providers.Factory(Service)
 
 
+# You can place marker on parameter default value
 @inject
-def main(service: Service = Provide[Container.service]) -> None:
-    ...
+def main(service: Service = Provide[Container.service]) -> None: ...
+
+
+# Also, you can place marker with typing.Annotated
+@inject
+def main_with_annotated(
+    service: Annotated[Service, Provide[Container.service]]
+) -> None: ...
 
 
 if __name__ == "__main__":
diff --git a/requirements-dev.txt b/requirements-dev.txt
index bc533741..0d759d4e 100644
--- a/requirements-dev.txt
+++ b/requirements-dev.txt
@@ -18,5 +18,6 @@ numpy
 scipy
 boto3
 mypy_boto3_s3
+typing_extensions
 
 -r requirements-ext.txt
diff --git a/src/dependency_injector/wiring.py b/src/dependency_injector/wiring.py
index b5247c9e..67d56f29 100644
--- a/src/dependency_injector/wiring.py
+++ b/src/dependency_injector/wiring.py
@@ -37,6 +37,21 @@ class GenericMeta(type): ...
 else:
     GenericAlias = None
 
+if sys.version_info >= (3, 9):
+    from typing import Annotated, get_args, get_origin
+else:
+    try:
+        from typing_extensions import Annotated, get_args, get_origin
+    except ImportError:
+        Annotated = object()
+
+        # For preventing NameError. Never executes
+        def get_args(hint):
+            return ()
+
+        def get_origin(tp):
+            return None
+
 
 try:
     import fastapi.params
@@ -572,6 +587,24 @@ def _unpatch_attribute(patched: PatchedAttribute) -> None:
     setattr(patched.member, patched.name, patched.marker)
 
 
+def _extract_marker(parameter: inspect.Parameter) -> Optional["_Marker"]:
+    if get_origin(parameter.annotation) is Annotated:
+        marker = get_args(parameter.annotation)[1]
+    else:
+        marker = parameter.default
+
+    if not isinstance(marker, _Marker) and not _is_fastapi_depends(marker):
+        return None
+
+    if _is_fastapi_depends(marker):
+        marker = marker.dependency
+
+        if not isinstance(marker, _Marker):
+            return None
+
+    return marker
+
+
 def _fetch_reference_injections(  # noqa: C901
     fn: Callable[..., Any],
 ) -> Tuple[Dict[str, Any], Dict[str, Any]]:
@@ -596,18 +629,10 @@ def _fetch_reference_injections(  # noqa: C901
     injections = {}
     closing = {}
     for parameter_name, parameter in signature.parameters.items():
-        if not isinstance(parameter.default, _Marker) and not _is_fastapi_depends(
-            parameter.default
-        ):
-            continue
+        marker = _extract_marker(parameter)
 
-        marker = parameter.default
-
-        if _is_fastapi_depends(marker):
-            marker = marker.dependency
-
-            if not isinstance(marker, _Marker):
-                continue
+        if marker is None:
+            continue
 
         if isinstance(marker, Closing):
             marker = marker.provider
diff --git a/tests/unit/samples/wiringfastapi/web.py b/tests/unit/samples/wiringfastapi/web.py
index 3cee5450..c1ed5102 100644
--- a/tests/unit/samples/wiringfastapi/web.py
+++ b/tests/unit/samples/wiringfastapi/web.py
@@ -1,7 +1,11 @@
 import sys
 
+from typing_extensions import Annotated
+
 from fastapi import FastAPI, Depends
-from fastapi import Request  # See: https://github.com/ets-labs/python-dependency-injector/issues/398
+from fastapi import (
+    Request,
+)  # See: https://github.com/ets-labs/python-dependency-injector/issues/398
 from fastapi.security import HTTPBasic, HTTPBasicCredentials
 from dependency_injector import containers, providers
 from dependency_injector.wiring import inject, Provide
@@ -28,11 +32,16 @@ async def index(service: Service = Depends(Provide[Container.service])):
     return {"result": result}
 
 
+@app.api_route("/annotated")
+@inject
+async def annotated(service: Annotated[Service, Depends(Provide[Container.service])]):
+    result = await service.process()
+    return {"result": result}
+
+
 @app.get("/auth")
 @inject
-def read_current_user(
-        credentials: HTTPBasicCredentials = Depends(security)
-):
+def read_current_user(credentials: HTTPBasicCredentials = Depends(security)):
     return {"username": credentials.username, "password": credentials.password}
 
 
diff --git a/tests/unit/samples/wiringflask/web.py b/tests/unit/samples/wiringflask/web.py
index f273d8aa..8bb44494 100644
--- a/tests/unit/samples/wiringflask/web.py
+++ b/tests/unit/samples/wiringflask/web.py
@@ -1,3 +1,5 @@
+from typing_extensions import Annotated
+
 from flask import Flask, jsonify, request, current_app, session, g
 from dependency_injector import containers, providers
 from dependency_injector.wiring import inject, Provide
@@ -26,5 +28,12 @@ def index(service: Service = Provide[Container.service]):
     return jsonify({"result": result})
 
 
+@app.route("/annotated")
+@inject
+def annotated(service: Annotated[Service, Provide[Container.service]]):
+    result = service.process()
+    return jsonify({"result": result})
+
+
 container = Container()
 container.wire(modules=[__name__])
diff --git a/tests/unit/wiring/test_fastapi_py36.py b/tests/unit/wiring/test_fastapi_py36.py
index 1e9ff584..491c991c 100644
--- a/tests/unit/wiring/test_fastapi_py36.py
+++ b/tests/unit/wiring/test_fastapi_py36.py
@@ -4,13 +4,17 @@
 
 # Runtime import to avoid syntax errors in samples on Python < 3.5 and reach top-dir
 import os
+
 _SAMPLES_DIR = os.path.abspath(
-    os.path.sep.join((
-        os.path.dirname(__file__),
-        "../samples/",
-    )),
+    os.path.sep.join(
+        (
+            os.path.dirname(__file__),
+            "../samples/",
+        )
+    ),
 )
 import sys
+
 sys.path.append(_SAMPLES_DIR)
 
 
@@ -37,6 +41,19 @@ async def process(self):
     assert response.json() == {"result": "Foo"}
 
 
+@mark.asyncio
+async def test_depends_with_annotated(async_client: AsyncClient):
+    class ServiceMock:
+        async def process(self):
+            return "Foo"
+
+    with web.container.service.override(ServiceMock()):
+        response = await async_client.get("/")
+
+    assert response.status_code == 200
+    assert response.json() == {"result": "Foo"}
+
+
 @mark.asyncio
 async def test_depends_injection(async_client: AsyncClient):
     response = await async_client.get("/auth", auth=("john_smith", "secret"))
diff --git a/tests/unit/wiring/test_flask_py36.py b/tests/unit/wiring/test_flask_py36.py
index 751f04d8..97420275 100644
--- a/tests/unit/wiring/test_flask_py36.py
+++ b/tests/unit/wiring/test_flask_py36.py
@@ -2,19 +2,25 @@
 
 # Runtime import to avoid syntax errors in samples on Python < 3.5 and reach top-dir
 import os
+
 _TOP_DIR = os.path.abspath(
-    os.path.sep.join((
-        os.path.dirname(__file__),
-        "../",
-    )),
+    os.path.sep.join(
+        (
+            os.path.dirname(__file__),
+            "../",
+        )
+    ),
 )
 _SAMPLES_DIR = os.path.abspath(
-    os.path.sep.join((
-        os.path.dirname(__file__),
-        "../samples/",
-    )),
+    os.path.sep.join(
+        (
+            os.path.dirname(__file__),
+            "../samples/",
+        )
+    ),
 )
 import sys
+
 sys.path.append(_TOP_DIR)
 sys.path.append(_SAMPLES_DIR)
 
@@ -29,3 +35,13 @@ def test_wiring_with_flask():
 
     assert response.status_code == 200
     assert json.loads(response.data) == {"result": "OK"}
+
+
+def test_wiring_with_annotated():
+    client = web.app.test_client()
+
+    with web.app.app_context():
+        response = client.get("/annotated")
+
+    assert response.status_code == 200
+    assert json.loads(response.data) == {"result": "OK"}