diff --git a/.github/workflows/release.yml b/.github/workflows/release.yml
index 6a578425..7ed44af1 100644
--- a/.github/workflows/release.yml
+++ b/.github/workflows/release.yml
@@ -72,15 +72,10 @@ jobs:
     runs-on: ${{ matrix.os }}
     strategy:
       matrix:
-        python-version: [3.5, 3.6, 3.7, 3.8, 3.9]
+        python-version: [3.6, 3.7, 3.8, 3.9]
         os: [ubuntu-20.04, macos-latest, windows-latest]
         arch: [x86_64]
         exclude:
-          # Python 3.5 is unable to properly
-          # find the recent VS tooling
-          # https://bugs.python.org/issue30389
-          - os: windows-latest
-            python-version: 3.5
           - os: windows-latest
             arch: aarch64
           - os: macos-latest
diff --git a/.github/workflows/tests.yml b/.github/workflows/tests.yml
index 469af2b2..e55e282b 100644
--- a/.github/workflows/tests.yml
+++ b/.github/workflows/tests.yml
@@ -17,14 +17,8 @@ jobs:
     # job.
     strategy:
       matrix:
-        python-version: [3.5, 3.6, 3.7, 3.8, 3.9]
-        os: [ubuntu-latest, macos-latest, windows-latest]
-        exclude:
-          # Python 3.5 is unable to properly
-          # find the recent VS tooling
-          # https://bugs.python.org/issue30389
-          - os: windows-latest
-            python-version: 3.5
+        python-version: [3.6, 3.7, 3.8, 3.9]
+        os: [ubuntu-latest, macos-latest, windows-latest]        
 
     runs-on: ${{ matrix.os }}
 
diff --git a/README.rst b/README.rst
index 4ee68b4d..2f5da7a4 100644
--- a/README.rst
+++ b/README.rst
@@ -13,7 +13,7 @@ of PostgreSQL server binary protocol for use with Python's ``asyncio``
 framework.  You can read more about asyncpg in an introductory
 `blog post <http://magic.io/blog/asyncpg-1m-rows-from-postgres-to-python/>`_.
 
-asyncpg requires Python 3.5 or later and is supported for PostgreSQL
+asyncpg requires Python 3.6 or later and is supported for PostgreSQL
 versions 9.5 to 13.  Older PostgreSQL versions or other databases implementing
 the PostgreSQL protocol *may* work, but are not being actively tested.
 
diff --git a/asyncpg/compat.py b/asyncpg/compat.py
index 6dbce3c9..348b8caa 100644
--- a/asyncpg/compat.py
+++ b/asyncpg/compat.py
@@ -6,52 +6,15 @@
 
 
 import asyncio
-import functools
-import os
 import pathlib
 import platform
 import sys
 
 
-PY_36 = sys.version_info >= (3, 6)
 PY_37 = sys.version_info >= (3, 7)
 SYSTEM = platform.uname().system
 
 
-if sys.version_info < (3, 5, 2):
-    def aiter_compat(func):
-        @functools.wraps(func)
-        async def wrapper(self):
-            return func(self)
-        return wrapper
-else:
-    def aiter_compat(func):
-        return func
-
-
-if PY_36:
-    fspath = os.fspath
-else:
-    def fspath(path):
-        fsp = getattr(path, '__fspath__', None)
-        if fsp is not None and callable(fsp):
-            path = fsp()
-            if not isinstance(path, (str, bytes)):
-                raise TypeError(
-                    'expected {}() to return str or bytes, not {}'.format(
-                        fsp.__qualname__, type(path).__name__
-                    ))
-            return path
-        elif isinstance(path, (str, bytes)):
-            return path
-        else:
-            raise TypeError(
-                'expected str, bytes or path-like object, not {}'.format(
-                    type(path).__name__
-                )
-            )
-
-
 if SYSTEM == 'Windows':
     import ctypes.wintypes
 
diff --git a/asyncpg/connection.py b/asyncpg/connection.py
index 3f678d16..4a656124 100644
--- a/asyncpg/connection.py
+++ b/asyncpg/connection.py
@@ -11,6 +11,7 @@
 import collections.abc
 import functools
 import itertools
+import os
 import sys
 import time
 import traceback
@@ -957,7 +958,7 @@ def _format_copy_opts(self, *, format=None, oids=None, freeze=None,
 
     async def _copy_out(self, copy_stmt, output, timeout):
         try:
-            path = compat.fspath(output)
+            path = os.fspath(output)
         except TypeError:
             # output is not a path-like object
             path = None
@@ -996,7 +997,7 @@ async def _writer(data):
 
     async def _copy_in(self, copy_stmt, source, timeout):
         try:
-            path = compat.fspath(source)
+            path = os.fspath(source)
         except TypeError:
             # source is not a path-like object
             path = None
@@ -1027,7 +1028,6 @@ async def _copy_in(self, copy_stmt, source, timeout):
         if f is not None:
             # Copying from a file-like object.
             class _Reader:
-                @compat.aiter_compat
                 def __aiter__(self):
                     return self
 
diff --git a/asyncpg/cursor.py b/asyncpg/cursor.py
index 978824c3..7ec159ba 100644
--- a/asyncpg/cursor.py
+++ b/asyncpg/cursor.py
@@ -7,7 +7,6 @@
 
 import collections
 
-from . import compat
 from . import connresource
 from . import exceptions
 
@@ -48,7 +47,6 @@ def __init__(
         if state is not None:
             state.attach()
 
-    @compat.aiter_compat
     @connresource.guarded
     def __aiter__(self):
         prefetch = 50 if self._prefetch is None else self._prefetch
@@ -206,7 +204,6 @@ def __init__(
         self._prefetch = prefetch
         self._timeout = timeout
 
-    @compat.aiter_compat
     @connresource.guarded
     def __aiter__(self):
         return self
diff --git a/asyncpg/pgproto b/asyncpg/pgproto
index 126bcd24..719c7c76 160000
--- a/asyncpg/pgproto
+++ b/asyncpg/pgproto
@@ -1 +1 @@
-Subproject commit 126bcd24bd3c59d581613dae026e2721efbedf16
+Subproject commit 719c7c76ee92988f094c447bae18b47ab04a2185
diff --git a/docs/index.rst b/docs/index.rst
index 77bf19f3..57031b03 100644
--- a/docs/index.rst
+++ b/docs/index.rst
@@ -14,7 +14,7 @@ PostgreSQL and Python/asyncio.  asyncpg is an efficient, clean implementation
 of PostgreSQL server binary protocol for use with Python's ``asyncio``
 framework.
 
-**asyncpg** requires Python 3.5 or later and is supported for PostgreSQL
+**asyncpg** requires Python 3.6 or later and is supported for PostgreSQL
 versions 9.5 to 13.
 
 Contents
diff --git a/setup.py b/setup.py
index b2fc8f33..606620cd 100644
--- a/setup.py
+++ b/setup.py
@@ -7,8 +7,8 @@
 
 import sys
 
-if sys.version_info < (3, 5):
-    raise RuntimeError('asyncpg requires Python 3.5 or greater')
+if sys.version_info < (3, 6):
+    raise RuntimeError('asyncpg requires Python 3.6 or greater')
 
 import os
 import os.path
@@ -259,7 +259,6 @@ def finalize_options(self):
         'Operating System :: MacOS :: MacOS X',
         'Operating System :: Microsoft :: Windows',
         'Programming Language :: Python :: 3 :: Only',
-        'Programming Language :: Python :: 3.5',
         'Programming Language :: Python :: 3.6',
         'Programming Language :: Python :: 3.7',
         'Programming Language :: Python :: 3.8',
@@ -268,7 +267,7 @@ def finalize_options(self):
         'Topic :: Database :: Front-Ends',
     ],
     platforms=['macOS', 'POSIX', 'Windows'],
-    python_requires='>=3.5.0',
+    python_requires='>=3.6.0',
     zip_safe=False,
     author='MagicStack Inc',
     author_email='hello@magic.io',
diff --git a/tests/test_copy.py b/tests/test_copy.py
index dd01153f..dcac96ac 100644
--- a/tests/test_copy.py
+++ b/tests/test_copy.py
@@ -13,7 +13,6 @@
 
 import asyncpg
 from asyncpg import _testbase as tb
-from asyncpg import compat
 
 
 class TestCopyFrom(tb.ConnectedTestCase):
@@ -467,7 +466,6 @@ class _Source:
                 def __init__(self):
                     self.rowcount = 0
 
-                @compat.aiter_compat
                 def __aiter__(self):
                     return self
 
@@ -507,7 +505,6 @@ class _Source:
                 def __init__(self):
                     self.rowcount = 0
 
-                @compat.aiter_compat
                 def __aiter__(self):
                     return self
 
@@ -533,7 +530,6 @@ class _Source:
                 def __init__(self):
                     self.rowcount = 0
 
-                @compat.aiter_compat
                 def __aiter__(self):
                     return self
 
@@ -564,7 +560,6 @@ def __init__(self, loop):
                     self.rowcount = 0
                     self.loop = loop
 
-                @compat.aiter_compat
                 def __aiter__(self):
                     return self